Correlation Between Gut Microbiota and Clinical Response to CAR-T Treatment for Hematological Malignancies
NCT06041815 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2023-09-18
Summary
The purpose of this prospective and observational study is to evaluate the correlation between gut microbiota and clinical response to CAR-T treatment for hematological malignancies
Conditions
- Hematological Malignancies
- Chimeric Antigen Receptor T-cell Therapy
Sponsors & Collaborators
-
The First Affiliated Hospital of Soochow University
lead OTHER
Principal Investigators
-
Xiaowen Tang, PhD · The First Affiliated Hospital of Soochow University
Eligibility
- Min Age
- 16 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-09-03
- Primary Completion
- 2024-09-02
- Completion
- 2025-03-02
Countries
- China
Study Locations
More Related Trials
-
A Real-World Study of Fecal Transplants for Cancer Therapy Side Effects
NCT07319364 ·Status: RECRUITING ·Phase: PHASE1
-
The Gut Microbiome and Immunotherapy Response in Solid Cancers
NCT06050733 ·Status: RECRUITING
-
Effect of Gut Microbiota and Its Metabolites on the Efficacy of Immunotherapy in Metastatic Colorectal Cancer
NCT06714903 ·Status: RECRUITING
-
A Study of LCAR-G08 in Subjects With Advanced Gastrointestinal Tumors Expressing Guanylyl Cyclase C (GCC)
NCT06197178 ·Status: TERMINATED ·Phase: PHASE1
-
Washed Microbiota Transplantation for the Treatment of Oncotherapy-Related Intestinal Complications
NCT04721041 ·Status: RECRUITING ·Phase: NA
-
Safety and Efficacy of CEA-targeted CAR-T for CEA-positive Advanced Malignant Solid Tumors
NCT05538195 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Gut Microbiota (GM) Biodiversity in Patients With Solid Tumors Treated With Immune Checkpoint Inhibitors (ICIs): a Monocenter Prospective Study to Identify the Interactions Between GM and ICIs
NCT07236983 ·Status: ACTIVE_NOT_RECRUITING
-
Analysis of Gut Microbiota in Patients With Brain Metastasis of Non-small Cell Lung Cancer Treated by Pembrolizumab Combined With Chemotherapy
NCT04333004 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Establishment of Individualized Immunotherapy Strategy and Platform Based on Changes of Intestinal Microbiota
NCT05065515 ·Status: UNKNOWN
-
Clinical Trial to Evaluate the Safety and Efficacy of IM96 CAR-T Cells Therapy in Patients With Advanced Digestive System Neoplasms
NCT05287165 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Gut Microbiota Reconstruction for NSCLC Immunotherapy
NCT05008861 ·Status: UNKNOWN ·Phase: PHASE1
-
A Metagenome-wide Association Study of Gut Microbiota in Gastrointestinal Non-Hodgkin's Lymphoma Patients
NCT03930043 ·Status: UNKNOWN
-
Fecal Microbiota Transplantation (FMT) in Patients With Advanced Gastric Cancer
NCT06346093 ·Status: RECRUITING ·Phase: NA
-
The Clinical Study of Adjuvant Chemotherapy on Intestinal and Urethral Flora in Patients With Gastric and Colon Cancer
NCT04198051 ·Status: UNKNOWN ·Phase: NA
-
FMT in Gut aGVHD Treated
NCT03148743 ·Status: RECRUITING
-
Role of the Gut Microbiome in the Outcome of Diffuse Large B-Cell Lymphoma Patients Treated With CAR-T Cell Therapy
NCT05725720 ·Status: RECRUITING
-
Clinical Study on the Safety and Preliminary Efficacy of CDH17/GUCY2C CAR-T in the Treatment of Patients With Advanced Colorectal Cancer
NCT07152210 ·Status: RECRUITING ·Phase: NA
-
CART Therapy in Digestive System Tumors
NCT04780529 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Multicenter Retrospective Study on Optimizing Combination Immunotherapy Strategies in MSS/MSI-L/pMMR Advanced Colorectal Cancer
NCT06849362 ·Status: ENROLLING_BY_INVITATION
-
MDT to Evaluate the Survival Benefit of Patients With Advanced Gastric / Colorectal Cancer
NCT03400657 ·Status: UNKNOWN
-
CAR-T Cell Immunotherapy in MUC1 Positive Solid Tumor
NCT02617134 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Clinical Study on the Safety and Efficacy of CAR-T Therapy for the TM4SF1-positive Tumors of Digestive System
NCT05673434 ·Status: UNKNOWN ·Phase: NA
-
Interaction Between Host, Microenvironment and Immunity on Gastrointestinal Neoplasms
NCT04363983 ·Status: RECRUITING ·Phase: NA
-
Universal CAR-T Cells (REVO-UWD-01) for Metastatic Colorectal Cancer
NCT06653010 ·Status: SUSPENDED ·Phase: EARLY_PHASE1
-
Circulating Tumor Cells (CTCs) in Advanced Gastric Cancer
NCT01848015 ·Status: UNKNOWN