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Effect of Probiotics on Primary Hypertension

NCT05095350 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 115

Last updated 2023-12-05

No results posted yet for this study

Summary

Gut microbiota was found to play a causal role in the pathogenesis of hypertension. Probiotics were shown to have a potential anti-hypertensive effect in human/rodent studies. This study aims to explore the effect, safety, and underlying mechanisms of the combination of probiotics, containing 10 strains from Lactobacillus and Bifidobacterium, on hypertension, compared with placebo.

Conditions

Interventions

BIOLOGICAL

Probiotic powder

Probiotic powder containing 10 strains from Lactobacillus and Bifidobacterium genus.

BIOLOGICAL

Placebo powder

Placebo powder containing maltodextrin and no probiotics.

Sponsors & Collaborators

  • Beijing Municipal Education Commission

    collaborator UNKNOWN

  • Chinese Academy of Medical Sciences, Fuwai Hospital

    lead OTHER

Principal Investigators

  • JUN CAI · Chinese Academy of Medical Sciences, Fuwai Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-12-05
Primary Completion
2023-06-02
Completion
2023-06-02

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05095350 on ClinicalTrials.gov