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Significance of Synbiotics on Inflammation and Proliferation of Colonic Mucosa

NCT01534572 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2012-02-16

No results posted yet for this study

Summary

There is a constant exchange between the gut epithelium and lumen, including microbial interplay. The aim of this study was to investigate dietary test products on inflammatory proliferation markers in the gut, and thereby if the products had positive effects in the gut as well as in other parts of the body.

The hypothesis was that the test products would reduce the inflammatory and proliferation activity of the gut epithelium by fermentation of normal food products and by converting dietary phenolic compounds into anti-inflammatory substances.

Conditions

Interventions

DIETARY_SUPPLEMENT

Lactobacillus

Intervention (2 weeks) with a strain of Lactobacillus

DIETARY_SUPPLEMENT

Bifidobacterium

Intervention (2 weeks) with a strain of Bifidobacterium

Sponsors & Collaborators

  • Region Skane

    lead OTHER

Principal Investigators

  • Bengt Jeppson, MD, PhD · Region Skåne

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-01-31
Primary Completion
2006-03-31
Completion
2012-02-29

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Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01534572 on ClinicalTrials.gov