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Gut Microbiota in Chronic GI Diseases

NCT06532110 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 260

Last updated 2024-08-01

No results posted yet for this study

Summary

The study involves characterizing the microbiota of patients with IBS, functional diarrhea, IBD, severe motility disorders and celiac disease.

This will be complemented by a translational phase of human-mouse hybrid experiments in which germ-free mice will be colonized with feces from these patients with different GI disease and non-disease controls and we will compare symptoms, microbiota composition and histological changes in the gut and in the brain of the mice.

Conditions

  • Microbiota

Interventions

OTHER

Endoscopy/Colonoscopy

Esophagogastroduodenoscopy and colonoscopy with video recording and biopsy collection

Sponsors & Collaborators

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-10-01
Primary Completion
2026-10-01
Completion
2026-11-01

Countries

  • Canada

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06532110 on ClinicalTrials.gov