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Food Reward Circuit Change by Orthodontics

NCT05026411 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2021-08-30

No results posted yet for this study

Summary

It has been described in obese individuals in which decreased basal metabolism as well as dopaminergic changes in the prefrontal cortex and striatum parallels the increased activation of reward brain regions in response to delicious food cues. Our aim is to explore different neurobehavioral dimensions of food choices and motivational processes in the light of this information, and to reveal whether these behaviors can be changed by operant conditioning with neuroimaging methods for phenotypes at risk.

Conditions

  • Eating Disorders
  • Eating Behavior
  • Eating Habit
  • Orthodontic Appliance Complication

Interventions

DIAGNOSTIC_TEST

T 0 Diffusion Tensor MR

Magnetic resonance images has been taken from 20 individuals with eating disorders before fixed orthodontic treatment

DIAGNOSTIC_TEST

T 1 Diffusion Tensor MR

Magnetic resonance images will be taken from 20 individuals with eating disorders after 12 months of orthodontic treatment.

DIAGNOSTIC_TEST

T 2 Diffusion Tensor MR

Magnetic resonance images will be taken from 20 individuals with eating disorders 6 months after orthodontic treatment finished

Sponsors & Collaborators

  • Muğla Sıtkı Koçman University

    collaborator OTHER

  • The Scientific and Technological Research Council of Turkey

    collaborator OTHER

  • Balikli greek hospital foundation

    collaborator UNKNOWN

  • Bezmialem Vakif University

    lead OTHER

Principal Investigators

  • Banu Kılıç · Bezmialem Vakif University

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-09-01
Primary Completion
2022-04-01
Completion
2022-11-01

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05026411 on ClinicalTrials.gov