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Lipid Metabolism in Obese Subjects Undergoing Bariatric Surgery

NCT04984785 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 68

Last updated 2021-08-02

No results posted yet for this study

Summary

The aim of the study is to evaluate modifications in the metabolism of polyunsaturated fatty acids (PUFA) and biosynthesis of the lipid mediators N-acylethanolamines (NAE), both known to induce and be induced by the nuclear peroxisome proliferator-activated receptor (PPAR)-α, which may also explain the well-established improved lipid and energy metabolism after bariatric surgery. The study is focused on understanding the weight loss mechanisms in order to develop targeted dietary protocols.

Conditions

  • Bariatric Surgery Candidate
  • Lipid Metabolism Disorders
  • Obesity

Sponsors & Collaborators

  • Azienda Ospedaliera Brotzu

    collaborator OTHER

  • University of Cagliari

    lead OTHER

Principal Investigators

  • Sebastiano Banni, PhD · Università di Cagliari

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-02-01
Primary Completion
2019-11-04
Completion
2020-09-07

Countries

  • Italy

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04984785 on ClinicalTrials.gov