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Effects of Gum Arabic on Metabolic Syndrome Parameters in Postmenopausal Women

NCT04978103 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2026-02-18

No results posted yet for this study

Summary

Gum Arabic ingestion has been proved to decrease some of the inflammatory markers in some metabolic diseases that have an inflammatory background. Nevertheless, the mechanism/s by which it does so is uncertain. This study is targeting one of the postulated molecular mechanisms at genetic level that may help to understand how Gum Arabic exerts its effect .The effects of GA on Nuclear Factor Kappa Beta, P38 Mitogen Activated Protein (MAP) Kinase levels, and on the expression of inflammatory cytokines genes are going to be assessed in postmenopausal females with Metabolic Syndrome.

Conditions

  • Metabolic Syndrome in Postmenopausal Females

Interventions

DRUG

Gum Arabic

A dietary supplement (Powdered exudates of Acacia Senegal (Gum Arabic E-414))

Sponsors & Collaborators

  • Ministry of Higher Education and Scientific Research, Republic of Sudan

    collaborator OTHER_GOV

  • University of Khartoum

    lead OTHER

Principal Investigators

  • Fatima Elhaj, PhD · lecturer in physiology department University of Khartoum

  • Shaza Elawad, MSc · lecturer in physiology department University of Khartoum

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
45 Years
Max Age
70 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-12-04
Primary Completion
2021-01-10
Completion
2022-12-20

Countries

  • Sudan

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04978103 on ClinicalTrials.gov