Early Warning Model of Susceptibility and High-risk Population of Cervical Cancer Related to HPV

NCT04974424 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 20000

Last updated 2021-07-23

No results posted yet for this study

Summary

Most uterine cervical high-risk human papillomavirus (HPV) infections are transient, with only a small fraction developing into cervical cancer. Family aggregation studies and heritability estimates suggest a significant inherited genetic component. Candidate gene studies and previous genome-wide association studies (GWASs) report associations between the HLA region and cervical cancer. Adopting a genome-wide approach, we aimed to establish an early warning model for a high-risk population of cervical cancer.

Conditions

Sponsors & Collaborators

  • Women's Hospital School Of Medicine Zhejiang University

    collaborator OTHER
  • Obstetrics & Gynecology Hospital of Fudan University

    collaborator OTHER
  • Qilu Hospital of Shandong University

    collaborator OTHER
  • Wuhan Central Hospital

    collaborator OTHER
  • Third Military Medical University

    collaborator OTHER
  • Xiangyang Central Hospital

    collaborator OTHER
  • Shenzhen Second People's Hospital

    collaborator OTHER
  • Huazhong University of Science and Technology

    lead OTHER

Principal Investigators

  • Ding Ma, MD, PhD · Huazhong University of Science and Technology

Eligibility

Min Age
25 Years
Max Age
75 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-01-01
Primary Completion
2023-12-01
Completion
2023-12-01

Countries

  • China

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04974424 on ClinicalTrials.gov