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HPV Integration and Tumorigenesis of Uterine Cervical Adenocarcinoma

NCT03742869 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2018-11-15

No results posted yet for this study

Summary

This study aims to analyze the multi-omics results between uterine cervical adenocarcinoma patients with and without human papillomavirus (HPV) infections. The multi-omics profiles include genome wide association study (GWAS), whole exome sequencing, analysis of transcriptomics and metabolomics. The HPV integration status is interpreted by GWAS. A comprehensive multi-omics will reveal the role of HPV integration in the molecular mechanism of tumorigenesis and prognosis of uterine cervical adenocarcinoma.

Conditions

  • Cervical Adenocarcinoma
  • Human Papillomavirus
  • Genome-wide Association Study
  • Whole Exome Sequencing
  • Transcriptome
  • Metabolome
  • Tumorigenesis
  • Prognosis

Interventions

COMBINATION_PRODUCT

A multi-omics analysis

A multi-omics analysis including genome-wide association study, whole exome sequencing, transcriptomics and metabolomics.

Sponsors & Collaborators

  • Lei Li

    lead OTHER

Principal Investigators

  • Lei Li, M.D. · Peking Union Medical College Hospital

Eligibility

Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-11-10
Primary Completion
2021-11-23
Completion
2021-11-23

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03742869 on ClinicalTrials.gov