Human Papilloma Virus (HPV) Circulating Tumor DNA (ctDNA) in Cervical Cancer
NCT04574635 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 18
Last updated 2025-10-27
Summary
This study collects blood samples to determine if the DNA of HPV that causes cervical cancer can be detected in patients with cervical cancer that is new (primary), has come back (recurrent), or has spread to other places in the body (metastatic) and are undergoing treatment with surgery, radiotherapy, chemotherapy, and/or immunotherapy. Researchers may use this information to predict response (good or bad) of the cervical cancer to treatment and detect recurrent cancer sooner.
Conditions
- Cervical Adenosquamous Carcinoma
- Cervical Squamous Cell Carcinoma, Not Otherwise Specified
- Infiltrating Cervical Carcinoma
- Metastatic Cervical Carcinoma
- Recurrent Cervical Carcinoma
- Stage I Cervical Cancer FIGO 2018
- Stage IA Cervical Cancer FIGO 2018
- Stage IA1 Cervical Cancer FIGO 2018
- Stage IA2 Cervical Cancer FIGO 2018
- Stage IB Cervical Cancer FIGO 2018
- Stage IB1 Cervical Cancer AJCC v8
- Stage IB2 Cervical Cancer FIGO 2018
- Stage IB3 Cervical Cancer FIGO 2018
- Stage II Cervical Cancer FIGO 2018
- Stage IIA Cervical Cancer FIGO 2018
- Stage IIA1 Cervical Cancer FIGO 2018
- Stage IIA2 Cervical Cancer FIGO 2018
- Stage IIB Cervical Cancer FIGO 2018
- Stage III Cervical Cancer FIGO 2018
- Stage IIIA Cervical Cancer FIGO 2018
- Stage IIIB Cervical Cancer FIGO 2018
- Stage IIIC Cervical Cancer FIGO 2018
- Stage IIIC1 Cervical Cancer FIGO 2018
- Stage IIIC2 Cervical Cancer FIGO 2018
- Stage IV Cervical Cancer FIGO 2018
- Stage IVA Cervical Cancer FIGO 2018
- Stage IVB Cervical Cancer FIGO 2018
Interventions
- PROCEDURE
-
Biospecimen Collection
Undergo collection of blood samples
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Allison E. Garda, MD · Mayo Clinic in Rochester
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-11-17
- Primary Completion
- 2025-09-10
- Completion
- 2027-11-30
Countries
- United States
Study Locations
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