Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous
NCT04947748 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2021-07-01
Summary
Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous is a prospective randomized controlled trial comparing 24 hour intravenous antibacterial therapy to 24 hour oral antibacterial therapy after surgery in complicated appendicitis.
Conditions
- Acute Appendicitis
- Acute Appendicitis With Rupture
- Acute Appendicitis Without Peritonitis
- Acute Appendicitis With Appendix Abscess
- Appendicitis; Perforation
- Appendicitis Perforated
- Appendicitis Acute
Interventions
- OTHER
-
Oral versus intravenous administration of antibacterial treatment
Mode of administration of antibacterial treatment
Sponsors & Collaborators
-
Tartu University Hospital
collaborator OTHER -
North Estonia Medical Centre
lead OTHER
Principal Investigators
-
Edgar Lipping, MD · North Estonia Medical Centre
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2020-11-01
- Primary Completion
- 2021-12-31
- Completion
- 2021-12-31
Countries
- Estonia
Study Locations
More Related Trials
-
Per Oral Versus Intravenous Postoperative Antibiotics After Surgery for Complicated Appendicitis.
NCT04803422 ·Status: COMPLETED ·Phase: NA
-
The Value of Post-operative Antibiotic Therapy After Laparoscopic Appendectomy for Complicated Acute Appendicitis (Other Than for Generalized Peritonitis)
NCT03688295 ·Status: RECRUITING ·Phase: PHASE3
-
Antibiotic Treatment Alone for Acute Simple Appendicitis in Children
NCT01356641 ·Status: COMPLETED ·Phase: NA
-
Acute Appendicitis and Microbiota - Etiology of Appendicitis and Antibiotic Therapy Effects
NCT03257423 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Initial Non-operative Treatment Strategy Versus Appendectomy Treatment Strategy for Simple Appendicitis in Children
NCT02848820 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Antibiotic Duration in Post-appendectomy Abscess
NCT03795194 ·Status: TERMINATED ·Phase: PHASE4
-
Acute Appendicitis: Active Observation With and Without Antibiotics
NCT03985514 ·Status: COMPLETED ·Phase: PHASE4
-
Role of Delay and Antibiotics on Perforation Rate While Waiting Appendectomy
NCT04378868 ·Status: COMPLETED ·Phase: PHASE4
-
Are Post-operative Antibiotics Indicated in Simple Appendicitis?
NCT01420367 ·Status: COMPLETED ·Phase: NA
-
Study of Conservative Versus Surgical Treatment of Appendicitis
NCT00469430 ·Status: COMPLETED ·Phase: PHASE2
-
Optimizing the Antibiotic Treatment of Uncomplicated Acute Appendicitis
NCT03236961 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Non Operative Treatment for Acute Appendicitis
NCT01096927 ·Status: COMPLETED ·Phase: PHASE4
-
A Retrospective Study of the Feasibility of Ambulatory Appendicectomy for Acute Appendicitis (Based on Data From the PMSI French National Hospital Information System) in the Adults Hospitalized Between December 2013 and December 2014
NCT02894086 ·Status: WITHDRAWN
-
Antibiotic Instillation in Appendicitis
NCT05470517 ·Status: COMPLETED ·Phase: PHASE2
-
Structured Management of Patients With Suspicion of Appendicitis Using a Clinical Score and Selective Imaging
NCT00971438 ·Status: TERMINATED ·Phase: NA
-
Conservative Versus Operative ManageMent of Acute Uncomplicated Appendicitis
NCT02916134 ·Status: COMPLETED ·Phase: NA
-
Laparoscopic Appendectomy for Uncomplicated Appendicitis: Does Antimicrobial Prophylaxis Really Matter?
NCT02404064 ·Status: UNKNOWN ·Phase: NA
-
Peri-appendiceal Abscess and Phlegmon in Acute Complicated Appendicitis Patients
NCT06490185 ·Status: NOT_YET_RECRUITING
-
Oral Antibiotic Outpatient Therapy vs. Placebo in the Treatment of Uncomplicated Acute Appendicitis
NCT06210269 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Polymerase Chain Reaction (PCR) and Cultivation of the Peritoneal Fluid at Operation for Appendicitis and Postoperative Enteral Antibiotic Treatment
NCT04713527 ·Status: UNKNOWN
-
Intravenous Versus Intravenous/Oral Antibiotics for Perforated Appendicitis
NCT00462020 ·Status: COMPLETED ·Phase: NA
-
Non-operative Management for Appendicitis in Children
NCT02795793 ·Status: UNKNOWN ·Phase: NA
-
Laparoscopic Antibiotic Lavage to Prevent Intra-abdominal Abscess Formation in Complicated Appendicitis
NCT06841003 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Appendicoliths in Acute Complicated Appendicitis Patients With Abscess
NCT06469086 ·Status: NOT_YET_RECRUITING
-
Inflammatory Parameters as Predictive Factors for Complicated Appendicitis
NCT05116124 ·Status: COMPLETED