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Laparoscopic Appendectomy for Uncomplicated Appendicitis: Does Antimicrobial Prophylaxis Really Matter?

NCT02404064 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 288

Last updated 2015-03-31

No results posted yet for this study

Summary

To compare surgical site infection (SSI) rate in patients undergoing laparoscopic appendectomy for acute uncomplicated appendicitis and treated with single dose regime of antibiotics versus group of patients undergoing laparoscopic appendectomy without antibiotics treatment. Patient will be given either single dose of perioperative antibiotics or no antibiotics before surgery.

Conditions

  • Appendicitis

Interventions

DRUG

cefamezin 1g IV

perioperative antibiotics (Cefamizin 1g IV; )

DRUG

metronidazole 500 mg IV

perioperative antibiotics (metronidazole 500 mg IV )

DRUG

Placebo

No perioperative antibiotics

Sponsors & Collaborators

  • HaEmek Medical Center, Israel

    lead OTHER

Principal Investigators

  • Dan Hershko, Professor · haemek medical center

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-03-31
Primary Completion
2015-03-31
Completion
2017-03-31

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Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02404064 on ClinicalTrials.gov