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Per Oral Versus Intravenous Postoperative Antibiotics After Surgery for Complicated Appendicitis.

NCT04803422 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 3193

Last updated 2024-10-01

No results posted yet for this study

Summary

The PIPA trial is a prospective, multicentre, cluster randomized cluster crossover non-inferiority study. We aim to test whether a three-day postoperative course of per oral antibiotics is non-inferior to a three-day postoperative course of intravenous antibiotics as standard care after laparoscopic surgery for complicated appendicitis in regards to the risk of postoperative intraabdominal abscess formation within 30-days

Conditions

  • Complicated Appendicitis

Interventions

DRUG

Antibiotic

The study aims to test whether oral antibiotics is non-inferior compared to intravenous antibiotics.

Sponsors & Collaborators

  • Zealand University Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-04-01
Primary Completion
2024-05-31
Completion
2024-06-30

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04803422 on ClinicalTrials.gov