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Olfactory and Taste Disturbances in Sjogren's Syndrome

NCT04909112 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2022-05-25

No results posted yet for this study

Summary

Sjögren syndrome is an autoimmune disease, responsible for xerostomia and xerophthalmia. Other organs and tissues can be affected: the skin, vaginal and nasal mucous membranes. As well, olfactory disorders have been also described in Sjögren syndrome.

Xerostomia often causes significant functional impairment of taste function. Impairment of taste function has been poorly evaluated in Sjögren syndrome like olfactory or (intra-nasal and oral) trigeminal disorders.

Conditions

  • Sjogren's Syndrome

Interventions

OTHER

Evaluation of olfactory function

Evaluation of olfactory function using olfactory detection thresholds

OTHER

Evaluation of taste function

Evaluation of taste function using taste detection thresholds

OTHER

Evaluation of (intra-nasal and oral) trigeminal functions

Evaluation of (intra-nasal and oral) trigeminal, interacting with olfactory and taste pathways, using odor and taste stimuli.

Sponsors & Collaborators

  • Université de Reims Champagne-Ardenne

    lead OTHER

Principal Investigators

  • Clovis FOGUEM, MD · Université de Reims Champagne-Ardenne

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-07-01
Primary Completion
2022-07-01
Completion
2022-10-01

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04909112 on ClinicalTrials.gov