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Malawi International Center of Excellence in Malaria Research School-based Cohort

NCT04858087 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 786

Last updated 2021-04-26

No results posted yet for this study

Summary

A school-based, prospective, cohort study was conducted to evaluate the epidemiology of P. falciparum (Pf) infections in school-age children and determine the impact of the screen-and-treat approach on Pf infection and anemia prevalence among students in two different transmission settings. Investigators aimed to evaluate how frequently malaria rapid diagnostic tests (mRDTs) fail to detect low-parasite-density infections as well as whether low-density infections contribute to the burden and health consequences of Pf infection in school-age children and whether they contain gametocytes, the parasite stage required for transmission from humans to mosquitos.

Conditions

Interventions

OTHER

Screening and treatment

Students were screened by mRDTs and treated with artemether-lumefantrine if positive

Sponsors & Collaborators

  • Kamuzu University of Health Sciences

    collaborator OTHER

  • Michigan State University

    collaborator OTHER

  • National Institute of Allergy and Infectious Diseases (NIAID)

    collaborator NIH

  • University of Maryland, Baltimore

    lead OTHER

Principal Investigators

  • Miriam Laufer, MD · University of Maryland, Baltimore

Eligibility

Min Age
5 Years
Max Age
15 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-03-24
Primary Completion
2015-11-13
Completion
2015-11-13

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04858087 on ClinicalTrials.gov