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Host RNA Profiles to Detect Infections in Young Infants

NCT04823026 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 152

Last updated 2022-12-28

No results posted yet for this study

Summary

This study seeks to identify and test host RNA expression profiles as markers for infections in young infants. Preliminary studies have shown high sensitivity and specificity for the discrimination of bacterial from non-bacterial infections in children, but the method has only been investigated in a limited number of young infants. The study aims to include 65 young infants with serious bacterial infections. The samples will be analysed by RNA sequencing. New diagnostic tools may help reduce unnecessary antibiotic treatment, antibiotic resistance, side-effects, hospitalisation and invasive procedures.

Conditions

Sponsors & Collaborators

  • Rigshospitalet, Denmark

    lead OTHER

Principal Investigators

  • Kia Hee Schultz Dungu, MD · Rigshospitalet, Denmark

  • Ulrikka Nygaard, Ass Prof PhD · Rigshospitalet, Denmark

Eligibility

Max Age
3 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-05-15
Primary Completion
2021-12-31
Completion
2021-12-31

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04823026 on ClinicalTrials.gov