Urinary tract infections are bacterial infections involving the urinary tract, including bladder, urethra, ureters, and kidneys. They are among the most common infections worldwide.
The World Health Organization published blueprints for urgently needed antibiotics targeting drug-resistant infections, while CARB-X awarded $1.2 million for novel antibiotic research and the FDA issued guidance on antibiotic duration limits in livestock.
University of Alberta researchers identified GlpG protease as a new drug target for treating antibiotic-resistant E. coli, which causes 250,000 UTI deaths annually. Inhibiting the protease prevented bacterial adhesion and biofilm formation in laboratory tests.
The CDC is investigating a multistate outbreak of extensively drug-resistant Salmonella Newport with an NDM-1 gene linked to Rosabella moringa powder capsules, marking the first documented outbreak of Salmonella with an NDM-1 gene in the United States.
Obesity contributes to about 1 in every 4 infectious disease deaths in the United States and 1 in 10 globally, according to a major study. People with obesity face 70% higher risk of hospitalization or death from infections, with risk tripling at severe obesity levels.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07559318 |
Post-Emergency Optimization of Antibiotic Therapy for Urinary Tract Infection (UTI) |
NOT_YET_RECRUITING | |
| NCT07555964 |
Comparing Clean Intermittent Self-catheterization and Indwelling Catheterization for the Management of Urinary Retention Before BPH Surgery. |
NOT_YET_RECRUITING | NA |
| NCT07507851 |
Electroacupuncture for the Prevention of Recurrent Lower Urinary Tract Infection in Women |
NOT_YET_RECRUITING | NA |
| NCT07501065 |
Prophylactic Antibiotics for Outpatient Urethral Bulking |
NOT_YET_RECRUITING | PHASE4 |
| NCT07438184 |
Periodontal Therapy and Genitourinary Inflammation in Patients With Prostatitis and Recurrent Urinary Tract Infections |
COMPLETED | NA |
| NCT07435844 |
Effect of Comprehensive Spa Care on Kidney and Urological Conditions: A Clinical Study in Adult Patients |
RECRUITING | NA |
| NCT07393711 |
Metaphylaxis of Infected Kidney Stones After Percutaneous Nephrolithotripsy |
NOT_YET_RECRUITING | NA |
| NCT07382271 |
Evaluation of Safety and Efficacy of Phage Therapy for Drug-resistant Bacterial Infections: An Exploratory, Prospective Single-arm Study |
NOT_YET_RECRUITING | NA |
| NCT07371429 |
A Study in Pediatric Participants Aged ≥2 to <12 Years With a Suspected or Confirmed Bacterial Infection or Receiving Prophylaxis Antibiotics |
NOT_YET_RECRUITING | PHASE1 |
| NCT07238673 |
Do Dynamic Urinary Leukocyte and Nitrite Changes Improve Risk Prediction for Infectious Complications Following PCNL? |
COMPLETED |
