Bacterial infections are illnesses caused by pathogenic bacteria invading tissues or organs. They range from mild localized infections to severe systemic disease and are typically treated with appropriate antibiotics when indicated.
Animal health markets are projected to expand in 2026, led by animal biotechnology at $34.6 billion to $36.19 billion and continued growth in veterinary antibiotics. Demand is being driven by companion animal care, livestock health, biologics R&D, and tighter oversight of antibiotic use.
The World Health Organization published blueprints for urgently needed antibiotics targeting drug-resistant infections, while CARB-X awarded $1.2 million for novel antibiotic research and the FDA issued guidance on antibiotic duration limits in livestock.
Acurx Pharmaceuticals announced a new clinical trial program for ibezapolstat in patients with recurrent C. difficile infection, building on Phase 2 results showing 96% clinical cure rates with no recurrence while sparing the gut microbiome.
Acurx Pharmaceuticals will discuss full year and fourth quarter 2025 financial results on March 13, 2026, and provide updates on ibezapolstat, its lead antibiotic candidate preparing for international Phase 3 trials for C. difficile infection.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07708116 |
First in Human Trial of CTX-187 in Healthy Volunteers and Chronically Infected Patients |
RECRUITING | PHASE1 |
| NCT07666230 |
Personalized Antibiotic Therapy - Point-of-Care Determination of Blood Levels of Beta-Lactam Antibiotics Using Coated-Blade-Spray Ion Mobility Spectrometry |
NOT_YET_RECRUITING | |
| NCT07648641 |
A Clinical Trial of the 13-Valent Pneumococcal Polysaccharide Conjugate Vaccine (CRM197/Tetanus Toxoid) |
NOT_YET_RECRUITING | |
| NCT07612163 |
Clinical Efficacy and Population Pharmacokinetics of β-lactams in Cirrhotic Patients |
RECRUITING | |
| NCT07607470 |
Large Algorithm Setting and Validation Study |
RECRUITING | |
| NCT07470541 |
Viromes in Infants Presenting With a Septic Syndrome |
NOT_YET_RECRUITING | NA |
| NCT07367295 |
Prospective Clinical Study, Using a Medical Device (RepHegyn) as an Adjuvant in the Treatment of Fungal (Candidiasis) and Bacterial Infections |
NOT_YET_RECRUITING | |
| NCT07207291 |
Phase I Study of Single/Multiple Ascending Doses of JKN2501 for Injection in Chinese Healthy Volunteers |
RECRUITING | PHASE1 |
| NCT07205575 |
AI-Guided Proteomic Biomarker Panel for Differentiating Bacterial and Viral Infections in Acute Febrile Illness |
COMPLETED | |
| NCT07146217 |
Pharmacokinetic and Safety Study of Metronidazole Oral Suspension in Pediatric Patients With Anaerobic Bacterial Infection |
NOT_YET_RECRUITING | PHASE2 |
