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Microbiome Influence on Seminal Quality

NCT04784260 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2023-03-13

No results posted yet for this study

Summary

The microbiome plays an important role in health and in some unknown etiologies. Some previous studies have identified bacteria in semen as a potential factor in male infertility. More studies are needed to discover associations between microbiomes and semen quality. In this study, forty semen samples from donors candidates will be collected where clinical criteria for seminal quality (volume, concentration, motility and morphology) will be measured and bacterial communities examined. With the next-generation sequencing of gene technology and bioinformatic analysis, we can investigate the associations between bacterial communities and seminal quality. It would be interesting to know if the proportion of certain bacteria is significantly higher in samples of normal seminal quality or significantly higher in samples of low seminal quality. This study could contribute to the current understanding of certain etiologies of male fertility.

Conditions

  • Infertility, Male

Interventions

OTHER

Microbiome analysis

Evaluate the bacterial composition in sperm from the different groups

Sponsors & Collaborators

  • Instituto Valenciano de Infertilidad, IVI Alicante

    lead OTHER

Principal Investigators

  • Elena Sellés, PhD · Instituto Valenciano de Infertilidad, IVI Alicante

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-06-01
Primary Completion
2023-01-12
Completion
2023-03-10

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04784260 on ClinicalTrials.gov