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The Association of Gut Microbiota and Spermatogenic Dysfunction

NCT05628987 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 306

Last updated 2024-07-24

No results posted yet for this study

Summary

This is a multicenter, case-control study that aims to investigate the relationship between microbiota and sperm quality via stool, blood, and urine microbiome, metabolomics, and collected clinical metadata. The results of the spermatogenic dysfunction, including aspermia, oligozoospermia, asthenozoospermia, and teratozoospermia, will be compared to normal basic semen analysis utilizing the World Health Organization (WHO) semen analysis procedure 5th edition.

Conditions

  • Infertility, Male
  • Azoospermia
  • Oligozoospermia
  • Asthenozoospermia
  • Teratozoospermia

Interventions

OTHER

no intervention

Observational studies, no intervention

Sponsors & Collaborators

  • National Natural Science Foundation of China

    collaborator OTHER_GOV

  • Zhujiang Hospital

    lead OTHER

Principal Investigators

  • Hongwei Zhou · Southern Medical University, China

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-02-20
Primary Completion
2025-06-30
Completion
2025-06-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05628987 on ClinicalTrials.gov