MedTrace Logo

Early Detection of Silent Myocardial Ischemia

NCT04680338 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1400

Last updated 2021-04-30

No results posted yet for this study

Summary

Early-Synergy investigates a diagnostic imaging approach in asymptomatic individuals from the general population for early detection of silent myocardial ischemia and cardiac dysfunction. The diagnostic imaging approach consists of cardiac computed tomography for coronary artery calcium scoring (CT-CAC) and cardiac magnetic resonance (CMR) stress perfusion imaging. Early-Synergy investigates the effect of early detection of silent myocardial ischemia and cardiac dysfunction by CMR in asymptomatic individuals with increased CAC. In addition, the diagnostic yield of CMR for early detection of silent myocardial ischemia and cardiac dysfunction is investigated. Asymptomatic individuals at increased risk (CAC ≥ 300) are therefore randomized 1:1 to either CMR stress perfusion imaging or a control group.

Conditions

Interventions

DIAGNOSTIC_TEST

CMR stress perfusion imaging

CMR stress perfusion imaging with feedback of clinically actionable findings to general practitioner and participant

Sponsors & Collaborators

  • Pim van der Harst

    lead OTHER

Principal Investigators

  • Pim van der Harst, MD, PhD · University Medical Center Groningen

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-05-27
Primary Completion
2021-12-31
Completion
2024-12-31

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04680338 on ClinicalTrials.gov