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High-flow Oxygen Therapy vs Non-invasive Ventilation: Comparison of Alveolar Recruitment in Acute Respiratory Failure

NCT04664322 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 16

Last updated 2020-12-11

No results posted yet for this study

Summary

This physiological study showed an increase in regional ventilation with NIV but no difference in alveolar recruitment as compared to HFNC in patients with hypoxemic ARF. Although NIV provided better oxygenation than HFNC, the effect on lung volumes could explain the potentially deleterious effect of NIV in hypoxemic ARF, reinforcing the recently developed concept of patient self-inflicted lung injury.

Conditions

  • Acute Respiratory Failure With Hypoxia

Interventions

DEVICE

non invasive ventilation and high flow nasal canulae oxygen therapy

patients with hypoxemic acute respiratory failure received alternatively non invasive ventilation and high flow nasal canulae oxygen therapy

Sponsors & Collaborators

  • University Hospital, Rouen

    lead OTHER

Principal Investigators

  • Christophe GIRAULT, MD · Medical Intensive Care Department, Rouen University Hospital, F-76000 Rouen, France

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-02-22
Primary Completion
2018-02-13
Completion
2018-02-19

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04664322 on ClinicalTrials.gov