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Short Term Physiological Effects of Nasal High Flow Oxygen on Respiratory Mechanics

NCT02363920 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 14

Last updated 2016-10-11

No results posted yet for this study

Summary

Nasal High Oxygen Flow (HOF) has been demonstrated to reduce the re-intubation rate in hypoxic patients and ameliorate breathing pattern in hypercapnic patients.

The aim of this study is to better understand the physiological mechanism underlying these results, assessing the respiratory mechanics in stable hypercapnic COPD patients.

Conditions

  • COPD
  • Chronic Hypercapnic Respiratory Failure

Interventions

DEVICE

HOF

the addition of high oxygen flow to patients breathing spontaneously

DEVICE

noninvasive mechanical ventilation (NIV)

the addition of a ventilatory support delivered with a oro-nasal interface

Sponsors & Collaborators

  • IRCCS Azienda Ospedaliero-Universitaria di Bologna

    lead OTHER

Principal Investigators

  • stefano nava, md · Sant'Orsola Malpighi Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-03-31
Primary Completion
2016-09-30
Completion
2016-09-30

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02363920 on ClinicalTrials.gov