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Oxygenation Methods and Non-invasive Ventilation in Patients With Acute Respiratory Failure and a do Not Intubate Order

NCT03673631 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 330

Last updated 2018-09-28

No results posted yet for this study

Summary

ICU care of patients considered "palliative" but without contraindications to admission to intensive care, for whom a do-not intubate order decision was made upon admission represents a particular target for non-invasive oxygenation techniques. The benefits of non invasive ventilation (NIV) in this population are debated especially in cancer patients. The more recently used nasal humidified high flux canula oxygenation (HFNC) therapy may have benefits over NIV in these patients. It is supposed to have better tolerance and could allow better compliance and thus higher efficiency. These potential benefits are major for such a population for which tolerance and symptomatic relief are priority goals

Conditions

  • Acute Respiratory Failure
  • Cancer
  • Hematologic Malignancy
  • Cardiac Insufficiency
  • Chronic Respiratory Insufficiency

Interventions

DEVICE

NIV

NIV setting: minimal FiO2 0.3; tidal volume 6-8ml/kg (theoretical body weight)

DEVICE

NFHC-O2

NFHC-O2 setting: minimal FiO2 0.3; minimal flow 40l/min

Sponsors & Collaborators

  • Poitiers University Hospital

    lead OTHER

Principal Investigators

  • René ROBERT, MD,PhD · Poitiers University Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-08-07
Primary Completion
2020-01-31
Completion
2020-01-31

Countries

  • France

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03673631 on ClinicalTrials.gov