MedTrace Logo

The Prognostic Impact of Selenium On Critical Surgical Patients

NCT04662242 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2023-02-10

No results posted yet for this study

Summary

Selenium is an important trace element for human for its multiple roles such as the antioxidant activity. Previous evidences showed that critically ill patients may benefit from selenium supplement but the dose and results are controversial.

Patients after operations for acute abdomen usually suffer from sepsis and stress. The aim of this study is to investigate the efficacy of selenium replacement in critical patients of acute abdomen, to see the impact on prognosis.

Conditions

  • Critical Illness
  • Selenium Deficiency
  • Trace Element Deficiency
  • Acute Abdomen
  • Sepsis

Interventions

DRUG

Selenium Supplement

Zelnite 400mcg/day in normal saline 100ml iv infusion for 7 days

DRUG

normal saline

normal saline 100ml iv infusion for 7 days

Sponsors & Collaborators

  • Chang Gung Memorial Hospital

    lead OTHER

Principal Investigators

  • Yu-Tung Wu, MD · Chang Gung Memorial Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-12-01
Primary Completion
2022-10-31
Completion
2022-11-16

Countries

  • Taiwan

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04662242 on ClinicalTrials.gov