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Effect of Antioxidant Vitamins on Coagulopathy and Nosocomial Pneumonia After Severe Trauma

NCT01897792 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 11

Last updated 2017-03-29

Study results available
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Summary

The purpose of this study is to determine the effect of antioxidant vitamins (vitamins C and E) on the development of coagulation derangements and nosocomial pneumonia after severe trauma in patients.

Conditions

  • Coagulopathy
  • Nosocomial Pneumonia

Interventions

DIETARY_SUPPLEMENT

Vitamin C

DIETARY_SUPPLEMENT

Vitamin E

DIETARY_SUPPLEMENT

Saline (for Vitamin C)

0.9% saline administered to mimic Vitamin C

DRUG

Placebo (for Vitamin E)

Sugar pill administered to mimic Vitamin E

Sponsors & Collaborators

  • University of Alabama at Birmingham

    lead OTHER

Principal Investigators

  • Jean-Francois Pittet, M.D. · The University of Alabama at Birmingham

  • Jeffrey Kerby, M.D., Ph.D. · The University of Alabama at Birmingham

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
19 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-05-31
Primary Completion
2015-02-28
Completion
2015-02-28

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01897792 on ClinicalTrials.gov