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Playful Multimodal Intervention, Monitoring and Decision Support for Activation of People With Alzheimer's Dementia

NCT04628702 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2024-07-05

No results posted yet for this study

Summary

The worldwide prevalence of dementia is increasing. Pharmaceutical therapies, at the best, slow the degenerative process, observable in Alzheimer's disease (AD). Additional approaches are therefore urgently needed to maintain the patient's independence and the abilities to execute activities of daily living to reduce the patient specific, familial and economic burden. Multimodal tablet-based training might be a potential linchpin in this quest. The primary aim of this study therefore is, to examine the efficacy of the tablet-based training program "Multimodal Activation" (MMA) in mild AD patients.

In a randomized controlled trial the investigators aim to include 220 mild AD patients, of which 110 are randomly assigned to the training group receiving guided tablet-based training for 1.5 years, and 110 to the control group. The multimodal intervention, as implemented in the training, includes physical, cognitive and social components. Efficacy of the training will be determined by means of between group pre-post comparison in quantitative neuropsychological and qualitative tests, MRI biomarker and blood biomarker.

Conditions

  • Alzheimer Disease

Interventions

BEHAVIORAL

tablet training

1.5 year training period

Sponsors & Collaborators

  • Joanneum Research Forschungsgesellschaft mbH

    collaborator OTHER

  • AustriaN Red Cross (OeRK)

    collaborator UNKNOWN

  • health system intelligence (HS & I)

    collaborator UNKNOWN

  • Medical University of Graz

    lead OTHER

Principal Investigators

  • Marisa Koini · Medical University of Graz, Department of Neurology

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
50 Years
Max Age
101 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-02-18
Primary Completion
2022-07-01
Completion
2023-01-31

Countries

  • Austria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04628702 on ClinicalTrials.gov