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Long-term Effects of the New Nordic Renal Diet in Patients With Moderate Chronic Kidney Disease

NCT04579315 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2024-04-12

No results posted yet for this study

Summary

As Chronic Kidney Disease (CKD) progresses normophosphatemia is maintained by increasing the per nephron urinary phosphorus excretion. Clinically, hyperphosphatemia is associated with high mortality, vascular calcification, endothelial dysfunction and progression of left ventricular hypertrophy. Currently the treatment of hyperphosphatemia is first being initiated in stage 5 and consists of dietetic guidance to avoid dietary phosphate and treatment with oral phosphate binders. However, studies have shown important side effects to phosphate binders in terms of progression of vascular calcifications. Therefore, it might be beneficial to start the dietetic treatment with a reduction of dietary phosphate earlier in the disease stage.

The aim of this project is to develop a New Nordic Renal Diet (NNRD) for CKD patients' stage 3-4 and to examine the long-term effects in a period of 26-weeks. NNRD has a high content of vegetable foods, less animal products and more local food items with a lesser content of phosphorus.

Conditions

  • Chronic Kidney Disease(CKD)
  • Hyperphosphatemia
  • Blood Pressure

Interventions

OTHER

Intervention group; NNRD group

The intervention is a whole food approach, meaning that the participants in the intervention group receives all daily food elements that they should consume

Sponsors & Collaborators

  • Bo Feldt-Rasmussen

    lead OTHER

Principal Investigators

  • Bo Feldt-Rasmussen, Professor · Department of Nephrology, Rigshospitalet, Copenhagen Denmark

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-11-30
Primary Completion
2022-08-30
Completion
2023-11-30

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04579315 on ClinicalTrials.gov