The Efficacy of Niacin on Hyperphosphatemia in Patients Undergoing Haemodialysis
NCT03163576 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 150
Last updated 2017-05-23
Summary
Hyperphosphatemia is a common complication of end-stage renal disease and particularly affects haemodialysis patients. Elevated serum phosphorus contributes to the development of secondary hyperparathyroidism, Mineral bone disorders,metastatic calcifications and calcific uremic arteriolopathy. There is a significant association between hyperphosphatemia and increased morbidity and mortality in end stage renal disease patients including cardiovascular morbidity and mortality ,also it's associated with hospitalization of haemodialysis patients.
Conditions
- Hyperphosphatemia
Interventions
- DRUG
-
Niacin
tablets
- DRUG
-
Phosphate Binder
tablets
Sponsors & Collaborators
-
Assiut University
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-06-30
- Primary Completion
- 2019-06-30
- Completion
- 2019-12-31
More Related Trials
-
Dietary Phosphorus Load and Postprandial Serum Phosphate in HD Patients
NCT04845724 ·Status: COMPLETED ·Phase: NA
-
Effectiveness of The Phosphate Mobile App on Serum Phosphorus in Adult Hemodialysis Patients With Hyperphosphatemia
NCT04789876 ·Status: COMPLETED ·Phase: NA
-
Effect of Restriction of Foods Containing Phosphorus Additives
NCT01965379 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of Cholestyramine in the Management of Hyperphosphatemia in Adult Hemodialysis Patients
NCT05577507 ·Status: COMPLETED ·Phase: PHASE4
-
Nicotinamide Versus Sevelamer Hydrochloride on Phosphatemia Control on Chronic Hemodialysed Patients
NCT01011699 ·Status: TERMINATED ·Phase: PHASE3
-
Effect of a Phosphate Modified Diet on Phosphate Balance and Phosphate Metabolism in Predialysis Patients Stage 3-4
NCT02073136 ·Status: COMPLETED ·Phase: NA
-
Phosphate Diet Strategies to Lower Blood Phosphate in Dialysis Patients
NCT07180069 ·Status: COMPLETED ·Phase: NA
-
The Impact of a Low or High Phosphate Diet on Phosphate and Calcium Excretion in Healthy People
NCT04013776 ·Status: UNKNOWN ·Phase: NA
-
Short-term Effect of a New Nordic Renal Diet on Phosphorus Homeostasis in CKD Stage 3-4
NCT03472105 ·Status: COMPLETED ·Phase: NA
-
Individualized Treatment of Hyperphosphatemia in Maintenance Hemodialysis Patients
NCT03861247 ·Status: COMPLETED ·Phase: PHASE3
-
The Influence of Low Phosphorus in Hemodialysis Patients
NCT04645459 ·Status: UNKNOWN ·Phase: NA
-
The Influence of Dietary Phosphorus Education Program on Nutritional Status and Serum Phosphate Level Among Hemodialysis Patient
NCT01245517 ·Status: UNKNOWN ·Phase: NA
-
Efficacy and Safety of Cinacalcet in Ca, P and iPTH Levels in Patients With Mild, Moderate and Severe SHPT
NCT03123406 ·Status: COMPLETED ·Phase: PHASE4
-
Effectiveness of Oral Alfacalcidol for Secondary Hyperparathyroidism in Chronic Hemodialysis Patients.
NCT02895061 ·Status: COMPLETED ·Phase: NA
-
Assessing How the Body Responds to Increased Phosphate Intake, and How This Response Depends on Age and Sex.
NCT07149337 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Parathyroid Hormone Levels in Relation to the Phosphorus Content of Meals
NCT00018135 ·Status: COMPLETED ·Phase: NA
-
Parathyroid Hyperplasia in Patients With Chronic Kidney Disease.
NCT03182517 ·Status: UNKNOWN
-
Activated Charcoal Use in Chronic Kidney Disease Patients
NCT06906874 ·Status: RECRUITING ·Phase: PHASE2
-
The Effect of Diuretics on Mineral and Bone Disorder in Chronic Kidney Disease Patients
NCT03082742 ·Status: UNKNOWN ·Phase: NA
-
Acute Changes in the Mineral Metabolism After a High Phosphorous Containing Meal in Dialysis Patients
NCT03868371 ·Status: COMPLETED ·Phase: NA
-
Acute Regulation of Parathyroid Hormone by Dietary Phosphate
NCT00037193 ·Status: COMPLETED
-
Study of Dietary Phosphate and Mineral Homeostasis in Early Chronic Kidney Disease
NCT00755690 ·Status: COMPLETED ·Phase: NA
-
Study Comparing Effects of Lanthanum Carbonate Versus Calcium Acetate Versus Dietary Phosphorus Restriction
NCT01357317 ·Status: UNKNOWN ·Phase: PHASE3
-
Alendronate for Vascular Calcification in Peritoneal Dialysis Patients?
NCT00299572 ·Status: UNKNOWN ·Phase: PHASE4
-
Dietary Phosphate and Serum Phosphorus
NCT02435017 ·Status: COMPLETED