Decreasing Intakes & Absorption of Phosphorus in Haemodialysis Patients Through Food Choices

Summary

Based on new evidence renal dietitians in Ireland are revising the diet sheet that is used to teach patients about reducing blood phosphate. Changes that renal dietitians plan to make to the dietary phosphorus prescription

* Inclusion of some nuts and pulses
* More detailed education re phosphate additives
* More accurate protein prescription
* Inclusion of more whole grains
* Encouraging the use of foods with a low phosphorus to protein ratio

The investigators want to test the two diet prescription to find out, which one is better at reducing blood phosphate and which one is more acceptable to patients. The investigators also want to make sure it is safe.

Conditions

• Renal Dialysis
• Hyperphosphatemia
• Dietary Modification

Interventions

OTHER

Current Low Phosphorus Diet Prescription

Routine / Standard Care: Routine dietary intervention is currently provided by one-to-one counselling to the subject and his/her relevant family members or carers, by a state registered dietitian regarding a diet which provides \<15mg Phosphorus /g Protein (over the day). This is equivalent to approximately 1000mg P / day. This is based on the 'Eating Well with Kidney Disease' dietsheet produced by the Renal Interest Group (RIG) of the Irish Nutrition \& Dietetic Institute (INDI) in 2010 and includes following main components: * Restricting protein intake to requirements (1-1.2g/kg Ideal Body Weight) * Restricting dairy intake (1-1.5 portions per day) * Avoiding foods high in phosphate * Avoiding foods with phosphate additives

OTHER

Modified Low Phosphorus Diet Prescription

Modified Low Phosphorus Diet Prescription: The new prescription recommends five changes to current management * Introduction of some plant protein in the form of pulses and nuts where the phosphorus is largely bound by phytate * Increased focus on avoiding additives * Introduction of more whole grains e.g. wholemeal sliced pan/ pasta/rice . * Avoiding over-prescription of protein which carries an obligatory phosphorus load. * Focus on high protein foods with a low phosphorus to protein ratio

Sponsors & Collaborators

• Cork University Hospital

  collaborator OTHER

• Irish Nutrition & Dietetic Institute

  collaborator UNKNOWN

• University College Cork

  lead OTHER

Principal Investigators

• Joseph Eustace, MB · HRB Clinical Research Facility

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2017-03-06

Primary Completion

2017-06-16

Completion

2017-06-16

Countries

• Ireland

Study Locations