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Efficacy of CONvalescent Plasma in Patients With COVID-19 Treated With Mechanical Ventilation

NCT04558476 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 475

Last updated 2024-10-29

No results posted yet for this study

Summary

The principal objective of the CONFIDENT trial is to assess the efficacy of two units (400-500 mL in total) of convalescent plasma, as compared to Standard of Care (SoC), to reduce day-28 mortality in patients with SARS-CoV-2 pneumonia who require mechanical ventilation.

Conditions

  • Covid19
  • Mechanical Ventilation Complication
  • Corona Virus Infection
  • Respiratory Failure
  • SARS (Severe Acute Respiratory Syndrome)

Interventions

BIOLOGICAL

Convalescent Plasma

2 units of convalescent plasma

OTHER

Standard of Care

Gold Standards

Sponsors & Collaborators

  • KCE Belgian Healthcare Knowledge Centre

    collaborator UNKNOWN

  • University of Liege

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-09-11
Primary Completion
2022-04-09
Completion
2023-03-09

Countries

  • Belgium

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04558476 on ClinicalTrials.gov