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Incidence of VAP in Patients With Severe COVID-19

NCT04766983 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 323

Last updated 2023-03-07

No results posted yet for this study

Summary

Combined retrospective and prospective cohort study to evaluate the incidence of microbiologically confirmed VAP in mechanically ventilated patients with COVID-19. In the retrospective part, microbiological data are based on bi-weekly surveillance ETA. In the prospective part, microbiological data are based on ETA and BAL performed on VAP suspicion. In the prospective part, immunological and virological analyses will be performed on biological samples (blood, respiratory tract) collected from patients at VAP diagnosis.

Conditions

  • Ventilator Associated Pneumonia
  • Covid19

Interventions

DIAGNOSTIC_TEST

bronchoalveolar lavage

BAL and ETA are performed as per clinical practice on clinical suspicion of VAP (Johanson score)

Sponsors & Collaborators

  • Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

    lead OTHER

Principal Investigators

  • Giacomo Grasselli, MD · Intensive Care Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation

  • Andrea Gori, MD · Infectious Diseases Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation

  • Mauro Panigada, MD · Intensive Care Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation

  • Alessandra Bandera, MD, PhD · Infectious Diseases Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-02-28
Primary Completion
2022-05-31
Completion
2023-01-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04766983 on ClinicalTrials.gov