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DXA Study of Precision and Reliability

NCT03621306 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 400

Last updated 2025-05-13

No results posted yet for this study

Summary

The purpose of the study is to assess precision of the GE Lunar iDXA, Hologic Horizon W DXA scanner, and the Stratec peripheral quantitative computed tomography (pQCT) scanner.

Aim 1: To assess standard deviation (SD) and coefficient of variation (CV) of testing bone mineral, bone geometry, and soft tissues in inanimate objects and adults. Tests on adults will be structured to assess:

1. Within- and between-day variability of testing
2. Within- and between-technician variability of testing
3. Variability due to positioning and post-scan processing
4. Variability due to different DXA scanning equipment

Aim 2: To assess the least significant change (LSC) for testing bone mineral and soft tissues in adults.

Aim 3: To assess strengths and limitations of DXA and pQCT testing, including sensitivity to movement, rate of re-rescanning, etc. which are crucial components for demonstrating feasibility in grant applications.

Aim 4: To construct a database of DXA and pQCT test results and quality control procedures, showing our laboratory's quality control level.

Conditions

  • Bone and Bones
  • Body Composition

Interventions

DEVICE

DXA and pQCT precision testing

The participants are only being observed; there is no intervention other than DXA and pQCT testing for the purposes of looking at instrument/technician precision..

Sponsors & Collaborators

  • Penn State University

    lead OTHER

Principal Investigators

  • Mary Jane De Souza, PhD · Penn State

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-06-16
Primary Completion
2028-08-31
Completion
2028-08-31
FDA Device
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03621306 on ClinicalTrials.gov