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Radiation Effects on Bone

NCT03134742 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2023-11-21

No results posted yet for this study

Summary

Post-radiotherapy fragility fractures (caused by weakened bones) are an occasional complication of orthopedic oncology of soft tissue sarcoma patients. Treatment for impending fracture due to radiotherapy does exist in the form of operative stabilization, to prevent the bone from breaking. Without the ability to predict those patients at a higher risk for fracture, indications for treatment are difficult to determine. This study is to determine if there is a correlation between patients undergoing radiotherapy for soft tissue sarcoma and loss of bone density. The study wll evaluate bone loss for short and long term fracture prediction using dual-energy xray, absorptiometry (DEXA \[DXA\]) and computerized tomography scans (CT Scans)

Conditions

  • Soft Tissue Sarcoma Adult

Interventions

OTHER

Control Group

No interventions this is the control group-no additional scans

DIAGNOSTIC_TEST

CT Scan

CT Scan of affected and contralateral limb

DIAGNOSTIC_TEST

DEXA Scans

DEXA Scan of affected and contralateral limb

DIAGNOSTIC_TEST

CT and DEXA Scans

CT Scan and DEXA Scan of affected and contralateral limb

Sponsors & Collaborators

  • State University of New York - Upstate Medical University

    lead OTHER

Principal Investigators

  • Timothy Damron, MD · State University of New York - Upstate Medical University

Eligibility

Min Age
18 Years
Max Age
89 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-03-13
Primary Completion
2025-04-13
Completion
2025-04-13

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03134742 on ClinicalTrials.gov