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Healthy Bones, Healthy Life: Habitual Physical Activity on Bone & Metabolic Health in Pediatric Cancer Survivors

NCT04472286 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2024-08-30

No results posted yet for this study

Summary

This project will examine habitual physical activity, bone health, and insulin resistance in pediatric acute lymphocytic leukemia (ALL) and lymphoma cancer survivors at two time points: baseline and 6 months. At the two study timepoints, all study participants will be asked to wear an accelerometer, receive a DXA scan of the lumbar spine and hip, and have blood drawn for analysis. Study participants will be given a gift card stipend for each study visit attended. Study visits will coincide with regular office visits to Children's Hospital Oncology Clinic and the Children's Hospital Survivorship Clinics whenever possible. The potential mechanism by which physical activity mediates bone changes will be explored by concurrently measuring changes in lean/fat mass and metabolic status. This pilot study will provide data to inform the design of a randomized controlled trial to test the effect of a physical activity intervention on bone health in PCS.

Conditions

  • Acute Lymphoblastic Leukemia, Pediatric
  • Pediatric ALL
  • Pediatric Lymphoma
  • Bone Loss
  • Metabolic Syndrome
  • Habitual Physical Activity
  • Precursor Cell Lymphoblastic Leukemia
  • Lymphoma
  • Leukemia
  • Lymphoid Leukemia
  • Pediatric
  • Osteoporosis
  • Osteoporosis Risk

Sponsors & Collaborators

  • University of Nebraska

    lead OTHER

Principal Investigators

  • Laura D Bilek, PhD · University of Nebraska

Eligibility

Min Age
5 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-11-01
Primary Completion
2024-05-30
Completion
2024-05-30

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04472286 on ClinicalTrials.gov