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Role of NLRP3 in Periodontitis and Diabetes

NCT04450810 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 133

Last updated 2021-01-26

No results posted yet for this study

Summary

NLRP3 plays a key role in endothelial function and may be a link for the known interaction of periodontitis and diabetes. The investigators compared the impact of gingival health, periodontitis (CP), diabetes or of both diseases (CP +diabetes) on saliva and serum NLRP3levels.

Conditions

  • Metabolic Disease
  • Periodontal Diseases

Interventions

OTHER

Observation of serum and salivary NLRP3 levels

Evaluation of serum and salivary NLRP3 levels

Sponsors & Collaborators

  • University of Messina

    lead OTHER

Principal Investigators

  • Giovanni Matarese · University of Messina

Eligibility

Min Age
35 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-06-01
Primary Completion
2017-09-18
Completion
2017-09-30

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04450810 on ClinicalTrials.gov