MedTrace Logo

Temporal Disorders in Left and Right Brain-Damaged Patients

NCT04424199 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 74

Last updated 2023-08-14

No results posted yet for this study

Summary

Time is an important function that permeates our everyday activities but it has been so far significantly under-investigated in neurological patients.

For instance, it is known that right brain damaged (RBD) patients with spatial attentional deficit (neglect) are impaired in both the ability to estimate the duration of an event (Time Estimation), showing a time underestimation, and the ability of mentally moving in past and future time (Mental Time Travelling), showing a deficit in processing future events when they are projected in the past. After a leftward shift of spatial attention induced by prismatic adaptation (PA), both the underestimation and the ability to travel in time ameliorate. However, less is known about these abilities in left brain damaged (LBD) patients.

Aims of this study are to investigate:

i) the performance (in terms of accuracy and reaction times) of LBD and RBD patients on Mental Time Travelling; ii) the correlation between Mental Time Travelling and Time Estimation abilities; iii) the efficacy of a single session of PA inducing a leftward (L-PA) and a rightward (R-PA) attentional shift on Mental Time Travelling and Time Estimation abilities.

A group of control subjects will be involved for comparison among groups.

Conditions

  • Brain Disease

Interventions

BEHAVIORAL

Rightward Attentional Shift (R-PA)

Patients will perform a session of 90 pointing movements toward a visual target presented on the right, the left or at the center of the visual field. This pointing task will be performed with prismatic googles inducing a rightward attentional shift.

BEHAVIORAL

Leftward Attentional Shift (L-PA)

Patients will perform a session of 90 pointing movements toward a visual target presented on the right, the left or at the center of the visual field. This pointing task will be performed with prismatic googles inducing a leftward attentional shift.

Sponsors & Collaborators

  • University of Bologna

    collaborator OTHER

  • Istituti Clinici Scientifici Maugeri SpA

    lead OTHER

Principal Investigators

  • Francesca Frassinetti, PhD · Istituti Clinici Scientifici Maugeri IRCCS

Eligibility

Min Age
45 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-02-01
Primary Completion
2022-12-31
Completion
2023-01-13

Countries

  • Italy

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04424199 on ClinicalTrials.gov