Hemodynamic Change of Coronary Atherosclerotic Plaque After Evolocumab Treatment
NCT04416425 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2021-04-21
Summary
Compelling evidences indicate that lipid-lowering therapy can reduce the high-risk plaque feathers and improve the coronary flow reserve. This study is going to investigate the change of lesion-specific hemodynamic significance as determined by ML(Machine Learning)-based CT-FFR (Computed Tomography-Fractional Flow Reserve)after Evolocumab treatment.
Conditions
Sponsors & Collaborators
-
Zibo Central Hospital
lead OTHER_GOV
Principal Investigators
-
Bo Li, Doctor · Zibo Central Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-07-30
- Primary Completion
- 2022-12-31
- Completion
- 2023-02-27
Countries
- China
Study Locations
More Related Trials
-
Impact of Coronary CT Angiography, Physiologic Assessment and Pharmacotherapy on the Clinical Outcomes
NCT04547231 ·Status: RECRUITING
-
Clinical Implication of 3-vessel Fractional Flow Reserve (FFR)
NCT01621438 ·Status: UNKNOWN
-
Evaluation of One-stop Strategy of EVAR and PCI
NCT03540342 ·Status: UNKNOWN ·Phase: NA
-
Epidemiology of Carotid IMT Progression in MESA - Ancillary Study
NCT00063440 ·Status: COMPLETED
-
Prospective Data Collection of IVMRI Cases
NCT00558441 ·Status: UNKNOWN ·Phase: NA
-
Assessment of Coronary Plaque Composition Using Optical Coherence Tomography
NCT01642173 ·Status: COMPLETED ·Phase: PHASE1
-
Angiography-Derived FFR And IVUS for Clinical Outcomes in Patients With Coronary Artery Disease
NCT04397211 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Haemodynamic and Geometric Factors in Atherosclerosis
NCT03044704 ·Status: ACTIVE_NOT_RECRUITING
-
Safety and Effectiveness of the Single-Use Coronary Forward Intravascular Lithotripsy Catheter Combined With the Intravascular Lithotripsy Therapy Device
NCT07109479 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Endothelial Function Guided Therapy in Patients With Non-obstructive Coronary Artery Disease
NCT04013204 ·Status: UNKNOWN ·Phase: NA
-
The AIPLAQUE Study: An Artificial Intelligence-based Prospective Study to Analyze PLAQUE Using CCTA
NCT05750082 ·Status: UNKNOWN
-
Contemporary Clinical Treatment and Long-term Outcomes in Patient With Coronary Chronic Total Occlusion
NCT03614559 ·Status: UNKNOWN
-
Correlation Between Coronary and Carotid Atherosclerotic Disease (CAD) and Links With Clinical Outcomes
NCT01353612 ·Status: COMPLETED
-
Fractional Flow Reserve Guided Immediate Versus Staged Complete Myocardial Revascularization in Patients With ST-segment Elevation Myocardial Infarction With Multivessel Disease (Future Study)
NCT05967663 ·Status: RECRUITING ·Phase: NA
-
Prediction of Atherosclerotic Plaque Progression
NCT05424705 ·Status: ACTIVE_NOT_RECRUITING
-
A Prospective Multicenter Clinical Study： IntracOronary neaR-Infrared Spectroscopy and OptIcal Coherence Tomography for Evaluating Coronary vulNerable Plaque in Patients With diabeTes
NCT06649305 ·Status: RECRUITING
-
Comprehensive Assessment of Morphometric, Functional, Biomechanical and Biological Interactions Between Atherosclerotic Plaque and Platelets Within the Stenosed Coronary Artery
NCT06275399 ·Status: RECRUITING
-
Establishment of a Cohort for Continuous Coronary Artery CTA Scanning and Predictive Analysis of Plaque Progression
NCT06660485 ·Status: NOT_YET_RECRUITING
-
Determination of the Duration of the Dual Antiplatelet Therapy by the Degree of the Coverage of The Struts on Optical Coherence Tomography From the Randomized Comparison Between Everolimus-eluting Stents Versus Biolimus A9-eluting Stents
NCT03873012 ·Status: NOT_YET_RECRUITING
-
Fractional Flow Reserve Derived From CT Related Treatment
NCT05319119 ·Status: UNKNOWN
-
Atherosclerosis-Progression in Coronary Arteries Compared to Periphery Vessels
NCT03164174 ·Status: ACTIVE_NOT_RECRUITING
-
The Effect of Subclinical Leaflet Thrombosis and Prosthesis Type on Transcatheter Aortic Valve Degeneration (POPular PET TAVI)
NCT05758662 ·Status: RECRUITING
-
Effectiveness of Interventional Therapy for Non-Flow-Limiting Vulnerable Plaques
NCT06855537 ·Status: RECRUITING ·Phase: PHASE4
-
Intravascular Imaging Study of the Effect of Inclisiran on Plaque in Patients With Acute Myocardial Infarction
NCT06372925 ·Status: RECRUITING ·Phase: PHASE4
-
Carotid Ultrasound Sub-Study of the Familial Atherosclerosis Study-observational Study
NCT00976014 ·Status: COMPLETED