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Intravascular Imaging Study of the Effect of Inclisiran on Plaque in Patients With Acute Myocardial Infarction

NCT06372925 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 334

Last updated 2026-04-14

No results posted yet for this study

Summary

This study is to evaluate the effect of Inclisiran on coronary atherosclerosis using intravascular ultrasound (IVUS) and optical coherence tomography (OCT) in patients with acute myocardial infarction and elevated low-density lipoprotein cholesterol (LDL-C).

Conditions

  • Plaque, Atherosclerotic

Interventions

DRUG

atorvastatin

20mg atorvastatin PO

PROCEDURE

IVUS/OCT

performed the IVUS/OCT at baseline and Day 360

DRUG

inclisiran

Inclisiran 284mg SC

Sponsors & Collaborators

Principal Investigators

  • Novartis Pharmaceuticals · Novartis Pharmaceuticals

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-07-09
Primary Completion
2026-12-30
Completion
2027-01-26

Countries

  • China

Study Locations

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Drugs
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06372925 on ClinicalTrials.gov