Brain Effects of Opiate Agonist and Antagonist
NCT04342130 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2021-05-07
Summary
This study will look at the short-term effect of morphine on brain response to food.
Conditions
- Chronic Low-back Pain
Interventions
- DRUG
-
Morphine
30 mg oral tablet
Sponsors & Collaborators
-
University of Rochester
lead OTHER
Principal Investigators
-
Paul Geha, MD · Department of Psychiatry in University of Rochester
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-04-27
- Primary Completion
- 2019-04-16
- Completion
- 2019-04-16
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Sensory Effects of Oral Opioid Treatment in Patients With Chronic Low Back Pain
NCT02824276 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate the Efficacy and Safety of ORAVESCENT Fentanyl Citrate for Management of Breakthrough Pain
NCT00214942 ·Status: COMPLETED ·Phase: PHASE3
-
Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms
NCT05142267 ·Status: RECRUITING ·Phase: NA
-
Opioid Modulation and Neural Reward Activation in Healthy Adults
NCT04854551 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study to Investigate of the Effects of Opioid Exposure on the Ability of the Diaphragm Muscle
NCT05856136 ·Status: RECRUITING ·Phase: PHASE4
-
Efficacy and Safety of Oxmorphone Extended Release in Chronic Non-malignant Pain
NCT00225797 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of Extended-release Oxymorphone Taken With or Without Food on Cognitive Functioning
NCT00930943 ·Status: COMPLETED ·Phase: PHASE4
-
Cannabidiol, Morphine, Pain
NCT04030442 ·Status: RECRUITING ·Phase: PHASE1
-
Efficacy and Safety Study of NKTR-181 in Opioid-Naive Subjects With Low Back Pain
NCT02362672 ·Status: COMPLETED ·Phase: PHASE3
-
Taste Acuity and Caloric Intake After Acute Morphine Administration
NCT01763697 ·Status: COMPLETED ·Phase: NA
-
Brain Response to Pain Control in People With Chronic Pain
NCT01878019 ·Status: COMPLETED
-
Investigation of Analgesic and Anti-hyperalgesic Effect of Opioids in Experimental Pain
NCT00647127 ·Status: COMPLETED ·Phase: PHASE3
-
Opiate-Induced Tolerance & Hyperalgesia in Pain Patients
NCT00246532 ·Status: COMPLETED ·Phase: PHASE4
-
Double Blind Randomized, Monocentric, Cross-over, Placebo-controlled Study to Evaluate the Effect of Morphine and Naloxone on Motivation (MBBAnalgesic)
NCT02267304 ·Status: COMPLETED ·Phase: PHASE2
-
The Role of Opioidergic Systems in Breathing Based Analgesia
NCT03419858 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Pain Response to Open Label Placebo in Induced Acute Pain in Healthy Male Adults
NCT03361579 ·Status: COMPLETED ·Phase: NA
-
Attention and Memory Disorders Related to Acute Morphine
NCT03507985 ·Status: UNKNOWN
-
The Effect of Oxytocin on Placebo Analgesia: an Experimental Study in Healthy Volunteers
NCT01886014 ·Status: COMPLETED ·Phase: NA
-
Ancillary Effects of Oral Naloxegol (Movantik)
NCT03235739 ·Status: COMPLETED ·Phase: PHASE4
-
Evaluation of the Interactions of Cannabidiol (CBD) With Morphine
NCT05143424 ·Status: RECRUITING ·Phase: PHASE1
-
A Brief Intervention for Patients on Opioids for Acute Pain
NCT05658926 ·Status: COMPLETED ·Phase: NA
-
Oxymorphone Extended Release in Patients With Cancer or Neuropathic Pain
NCT00911261 ·Status: COMPLETED ·Phase: PHASE3
-
Understanding How Opioids Affect the Experiential and Neural Signatures of Social Experiences
NCT05007561 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Orphenadrine and Methocarbamol for LBP
NCT02665286 ·Status: COMPLETED ·Phase: PHASE4
-
Study to Evaluate the Efficacy and Safety of ORAVESCENT Fentanyl Citrate for the Management of Breakthrough Pain
NCT00214955 ·Status: COMPLETED ·Phase: PHASE3