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Taste Acuity and Caloric Intake After Acute Morphine Administration

NCT01763697 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2014-05-29

No results posted yet for this study

Summary

This study will investigate the effects of acute morphine administration on taste acuity and how much a person eats. It is hypothesized that there will be a dose dependent decrease in taste acuity and dose dependent increase in food intake associated with acute morphine administration. Knowledge from this study will impact the future of feeding behavior and obesity research in the general population. Results will also promote exploration of the long-term effect of opioid abuse on taste acuity and feeding behavior in substance abusing populations.

Conditions

  • Taste Sweet
  • Taste Salty
  • Feeding Behavior

Interventions

BEHAVIORAL

taste acuity assessment

Quantitative measurement of for tasting detection and recognition thresholds, magnitude of perception and hedonic response.

BEHAVIORAL

Recorded meal

Sponsors & Collaborators

Principal Investigators

  • Denis G Antoine, M.D. · Johns Hopkins University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-03-31
Primary Completion
2014-05-31
Completion
2014-05-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01763697 on ClinicalTrials.gov