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Probiotic-Muscle Study

NCT04297111 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2022-11-03

No results posted yet for this study

Summary

This study will examine the effect of probiotic supplementation (Bacillus coagulans) on muscle protein synthesis in older adults in response to a plant-based diet.

The investigators hypothesize that probiotic supplementation will enhance the digestibility of plant protein, therefore increasing the proportion of ingested amino acids that appear in systemic circulation and enhancing rates of muscle protein synthesis.

Conditions

  • Old Age; Debility
  • Muscle Weakness
  • Protein Deregulation
  • Protein Deposition

Interventions

DIETARY_SUPPLEMENT

Probiotic

GanedenBC30 (Bacillus coagulans GBI-30, 6086) capsule made of 1 billion colony forming units (cfu). Description: pure cell mass of an L-(+) lactic acid-producing, gram-positive, spore-forming shaped bacterium that is aerobic to microaerophilic. Maltodextrin used as filler.

OTHER

Placebo

Maltodextrin capsule, no active ingredient

Sponsors & Collaborators

  • Kerry Group

    collaborator UNKNOWN

  • University College Dublin

    lead OTHER

Principal Investigators

  • Helen Roche, PhD · University College Dublin

  • Caoielann Murphy, PhD · University College Dublin

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-11-25
Primary Completion
2020-10-03
Completion
2021-12-01

Countries

  • Ireland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04297111 on ClinicalTrials.gov