Memory Retrieval and Encoding Investigated by Neural Stimulation
NCT04286776 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 800
Last updated 2024-11-05
Summary
The purpose of this research is to understand biomarkers of human memory through correlational analyses and to use focal electrical stimulation as a causal manipulation to understand how biomarkers of memory relate to other brain states and behavioral measures.
Conditions
- Epilepsy Intractable
Interventions
- DEVICE
-
Direct electrical stimulation
Stimulation will not exceed 0.75 mA and will be approved prior by study investigators. Each subject will have a safety threshold testing at the beginning of each session and if 'afterdischarges' occur the subject's stimulation threshold will be lowered.
Sponsors & Collaborators
-
National Institute of Neurological Disorders and Stroke (NINDS)
collaborator NIH - collaborator OTHER
- lead OTHER
Principal Investigators
-
Michael Kahana, PhD · University of Pennsylvania
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-10-12
- Primary Completion
- 2024-12-31
- Completion
- 2024-12-31
- FDA Device
- Yes
Countries
- United States
Study Locations
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