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Neurotoxicity of Anesthesia in Middle Aged Patients

NCT04275531 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 600

Last updated 2022-03-15

No results posted yet for this study

Summary

for the last 20 years, the increasing reports from non-human studies have raised suspicion that general anesthetics may cause neurotoxic changes in the developing brain that lead to adverse neurodevelopmental outcomes later in life.there are several case reports of reversible smell and taste dysfunction following exposure to general anesthesia suggesting a possible relationship between anesthetic agents and olfactory dysfunction.

this study is to assess the possible neurotoxicity of sevoflurane,isoflurane,and propofol based anesthesia guided by olfactory changes

Conditions

  • Anesthesia; Adverse Effect

Interventions

DRUG

Anesthesia Agent

various anesthetic agents used in both general and regional anesthesia

Sponsors & Collaborators

  • Tanta University

    lead OTHER

Principal Investigators

  • Mona R Elghamry, MD · Tanta University, Faculty of Medicine

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-03-01
Primary Completion
2022-08-01
Completion
2022-09-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04275531 on ClinicalTrials.gov