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The Hemodynamic Effects of CGRP After Glibenclamide Administration in Healthy Volunteers

NCT04231617 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2020-09-09

No results posted yet for this study

Summary

To investigate the hemodynamic effects of CGRP after glibenclamide administration.

Conditions

  • Hemodynamics of Cranial Arteries
  • Headache
  • Cerebral Blood Flow

Interventions

DRUG

glibenclamide

Oral administration of glibenclamide or placebo. To investigate the role of CGRP on cranial arteries in healthy volunteers after glibenclamide/placebo administration .

DRUG

CGRP infusion

CGRP infusion

DRUG

Placebo

placebo

Sponsors & Collaborators

  • Danish Headache Center

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-01-20
Primary Completion
2020-08-01
Completion
2020-09-01

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04231617 on ClinicalTrials.gov