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Pretreatment With Sumatriptan on Cilostazol Induced Headache in Healthy Volunteers

NCT03156920 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2017-10-19

No results posted yet for this study

Summary

To develop a pragmatic migraine model the investigators will induce headache in healthy volunteers with a phosphodiesterase inhibitor (cilostazol). The participants will be pre-treated with sumatriptan. If the headache responds to sumatriptan, the model can be used to test new drug candidates.

Conditions

Interventions

DRUG

Placebo

Cilostazol is given both study days to induce headache. One day the headache is treated with placebo and the other day with sumatriptan

DRUG

Sumatriptan

Cilostazol is given both study days to induce headache. One day the headache is treated with placebo and the other day with sumatriptan

Sponsors & Collaborators

  • Danish Headache Center

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-05-23
Primary Completion
2017-10-18
Completion
2017-10-18

Countries

  • Denmark

Study Locations

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Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03156920 on ClinicalTrials.gov