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The Effect of Sumatriptan and Placebo Injection on Cilostazol Induced Headache

NCT03422796 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2020-01-29

No results posted yet for this study

Summary

To develop a pragmatic migraine model the investigators will induce headache in patients with migraine without aura with a phosphodiesterase inhibitor (cilostazol). If the headache responds to sumatriptan injection, the model can be used to test new drug candidates.

Conditions

Interventions

DRUG

Cilostazol 200mg

Cilostazol is given both study days to induce headache. One day the headache is treated with placebo and the other day with sumatriptan

DRUG

SUMAtriptan 6 MG/ML

Cilostazol is given both study days to induce headache. One day the headache is treated with placebo and the other day with sumatriptan

DRUG

Placebo

Cilostazol is given both study days to induce headache. One day the headache is treated with placebo and the other day with sumatriptan

Sponsors & Collaborators

  • Danish Headache Center

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-11-01
Primary Completion
2018-09-01
Completion
2018-09-01

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03422796 on ClinicalTrials.gov