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Migraine With Aura Inducing Characteristics and Effects on the Cerebral Arteries and Blood Flow by Hypoxia

NCT01896167 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2015-02-12

No results posted yet for this study

Summary

In this study the investigators will investigate the following hypothesis

* that hypoxia induce migraine headache and migraine aura
* the aura phase is associated with a spreading reduction in cerebral blood flow
* the migraine headache is associated with dilatation of intra- and extracerebral arteries
* the migraine headache is associated with changes in brain metabolism
* the pre-ictal stage of a migraine attack with aura is associated with specific patterns in neural activity.

Conditions

Interventions

OTHER

Hypoxia

Inhalation of hypoxic air (8-12% oxygen content)

OTHER

Placebo

Inhalation of atmospheric air

Sponsors & Collaborators

  • Danish Headache Center

    lead OTHER

Principal Investigators

  • Nanna Arngrim, MD · Department of Neurology, Glostrup Hospital

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-04-30
Primary Completion
2014-09-30
Completion
2014-09-30

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01896167 on ClinicalTrials.gov