Headache Inducing Effect of Cromakalim in Migraine Patients
NCT03228355 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16
Last updated 2018-06-19
Summary
To investigate the role of KATP channels on the cerebral hemodynamic in migraine patients.
Conditions
- Headache, Migraine
Interventions
- DRUG
-
Levcromakalim
To investigate the role of Levcromakalim on cerebral hemodynamic in migraine patients
- DRUG
-
Saline
To investigate the role of levcromakalim compared with saline cerebral hemodynamic in migraine patients.
Sponsors & Collaborators
-
Danish Headache Center
lead OTHER
Principal Investigators
-
Messoud Ashina, Professor · DHC
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- QUADRUPLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-05-24
- Primary Completion
- 2017-11-30
- Completion
- 2017-11-30
Countries
- Denmark
Study Locations
More Related Trials
-
Headache Inducing Effect of NN414 in Migraine Patients
NCT04744129 ·Status: UNKNOWN ·Phase: NA
-
Transcriptomic and Biochemical Changes During a Migraine Attack
NCT02468622 ·Status: COMPLETED
-
Carbachols Headache-inducing Effect and Changes in Cerebral Blood Flow in Migraine Patients
NCT00564408 ·Status: COMPLETED ·Phase: NA
-
Effect of Levcromakalim in Individuals With Migraine Pretreated With Erenumab
NCT05889442 ·Status: COMPLETED ·Phase: NA
-
Effect of Sumatriptan on Levcromakalim-Induced Symptoms in Individuals With Migraine
NCT05211050 ·Status: COMPLETED ·Phase: NA
-
The Hemodynamic Effects of CGRP After Glibenclamide Administration in Healthy Volunteers
NCT04231617 ·Status: COMPLETED ·Phase: NA
-
The Hemodynamic Effects of PACAP38 After Glibenclamide Administration in Healthy Volunteers
NCT04960657 ·Status: COMPLETED ·Phase: NA
-
The Effect of Glyceryl Trinitate and Diamox on Cerebral Haemodynamics.
NCT00363571 ·Status: UNKNOWN ·Phase: NA
-
PACAP38´s (Pituitary Adenylate Cyclase-Activating Polypeptide) Headache Inducing Characteristics and Effects on the Cerebral Blood Flow
NCT00380263 ·Status: COMPLETED ·Phase: NA
-
PGI2 Induced Headache and Cerebral Haemodynamics in Healthy Volunteers
NCT00291395 ·Status: TERMINATED ·Phase: PHASE1
-
Natriuretic Peptide's Headache Inducing Characteristics and Effects on the Cerebral Blood Flow
NCT01637662 ·Status: COMPLETED ·Phase: NA
-
Clinical Characteristics and Pathophysiology of Post-Traumatic Headache
NCT03791515 ·Status: COMPLETED ·Phase: NA
-
Carbachol´s Headache Inducing Characteristics and Effects on the Cerebral Blood Flow
NCT00357864 ·Status: COMPLETED
-
Headache Inducing Characteristics and Possible Changes in Cerebral Blood Flow After Administration of PGE2
NCT00374530 ·Status: COMPLETED ·Phase: NA
-
Calcitonin Gene Related Peptide-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2.
NCT00358839 ·Status: COMPLETED ·Phase: NA
-
The Effect of PACAP27 on the Extra- and Intracerebral Arteries Assessed by Magnetic Resonance Angiography (MRA) on Healthy Volunteers
NCT03560024 ·Status: COMPLETED ·Phase: NA
-
Hypersensitivity to PACAP-38 in Post-Traumatic Headache
NCT05378061 ·Status: UNKNOWN ·Phase: NA
-
Glyceryl-Trinitrate-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2
NCT00257985 ·Status: COMPLETED ·Phase: NA
-
Glyceryl-Trinitrate-Induced Headache in Patients With Familial Hemiplegic Migraine
NCT00541736 ·Status: COMPLETED ·Phase: NA
-
1H Magnetic Resonance Spectroscopy in Migraine Patients
NCT04220606 ·Status: COMPLETED ·Phase: NA
-
Hypersensitivity to Phosphodiesterase 5 Inhibition in Post-Traumatic Headache
NCT05669885 ·Status: UNKNOWN ·Phase: NA
-
Prophylactic Effect of Memantine in Chronic Tension-Type Headache
NCT00315666 ·Status: COMPLETED ·Phase: PHASE3
-
Hypersensitivity to Opening of BKCa Channels in Post-Traumatic Headache
NCT05378074 ·Status: UNKNOWN ·Phase: NA
-
Effect of Acetyl-L-carnitine in Migraine
NCT01695317 ·Status: COMPLETED ·Phase: PHASE4
-
Cabergoline as a Preventive Treatment for Chronic Migraine
NCT05525611 ·Status: COMPLETED ·Phase: NA