MedTrace Logo

The Physiological Effect of High Flow Oxygen Therapy

NCT04212182 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2019-12-30

No results posted yet for this study

Summary

Although non-invasive positive pressure ventilation (NPPV) shows the good curative effect of treating the patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD), some patients do not tolerate NPPV or do not benefit from it. High-flow nasal cannula (HFNC) is well tolerated and may be used to patients with AECOPD who are intolerant to NPPV treatment. This study is to evaluate the physiological effect of HFNC and compare it with NPPV.

Conditions

  • High-flow Nasal Cannula
  • Non-invasive Positive Pressure Ventilation
  • Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Interventions

DEVICE

HFNC

HFNC provides warmed and humidified gas administered through slightly enlarged nasal prongs.

DEVICE

NPPV

NPPV is the standard therapy for ventilatory failure in AECOPD.

Sponsors & Collaborators

  • The First Affiliated Hospital of Guangzhou Medical University

    lead OTHER

Principal Investigators

  • Rongchang Chen, MD · The First Affiliated Hospital of Guangzhou Medical University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-12-27
Primary Completion
2020-07-01
Completion
2020-07-01

Countries

  • China

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04212182 on ClinicalTrials.gov